Christina Applegate, the Emmy Award-winning star from iconic films like Anchorman: The Legend of Ron Burgundy and Bad Moms, finds herself navigating another turbulent chapter in her life after recently addressing her hospitalization. Often compared to the unpredictable nature of Venus retrograde, which can throw our lives into delightful disarray, Applegate’s journey through her diagnosis of multiple sclerosis (MS) is a testament to resilience in the face of uncertainty. The actress, who has openly shared her health battles since her diagnosis, took to Instagram to express gratitude for her supporters, reminding us how the cosmos can align to bring unexpected comfort during difficult times. As we delve deeper into her story, reflecting on her experiences with vulnerability and strength, one can’t help but wonder: how do the stars influence our ability to overcome life’s challenges? Join me in exploring Applegate’s compelling journey and her latest memoir, You With the Sad Eyes—a raw and honest account of her life and struggles. LEARN MORE.

Christina Applegate has addressed reports that she was hospitalised last week.

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The Emmy Award-winning actor, known for her roles in Anchorman: The Legend of Ron Burgundy and Bad Moms, announced in 2021 that she had been diagnosed with multiple sclerosis (MS).

According to the NHS, the incurable condition affects the brain and spinal cord, causing a wide range of symptoms including problems with vision, arm or leg movement, sensation or balance.

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Applegate, who recently released her memoir You With the Sad Eyes, is speaking out for the first time since reports of her recent hospitalisation.

Taking to Instagram, the 54-year-old shared a message alongside a photo of a white ‘Kissy Kissy’ labelled coffee cup sitting on top of her memoir.

“Thank you for the outpouring of love and well wishes,” she penned on Monday (20 April).

Christina Applegate speaking onstage in 2025 (Kevin Winter/Getty Images)

“Health issues are a constant for me, but I’m a strong chick and I’m getting stronger and better every day.

“I’m taking a moment to focus on my health, but I’ll be back with more to say soon enough.”

Applegate previously explained that she started experiencing symptoms like leg buckling and numbness seven years before her diagnosis in 2016.

“You can fall, you can slip, your legs can buckle,” she told Good Morning America in 2023.

Applegate in 2004, the year Anchorman was released (Mike Guastella/WireImage)

“There are just certain things that people take for granted in their lives that I took for granted.

“Going down the stairs, carrying things — you can’t do that anymore.”

You With the Sad Eyes promises to provide a ‘full story of her years in the public eye’ as a ‘childhood star turned iconic comedic actress’.

In the book, Applegate opens up about ‘painful moments the public didn’t see — abuse, abandonment, insecurities, self-doubt, body dysmorphia, assault’.

Applegate started having symptoms seven years before her multiple sclerosis (MS) diagnosis (Kevin Winter/Getty Images)

“I wrote this because I truly believe that books can make people feel less alone. I promise, You with the Sad Eyes won’t be some big violin scratching for my life. But it will be real,” she said ahead of its release last month.

“It will be filled with the ups and downs, the humour and grief of life. So here I am. Real me. Lots to say.”

The Married… with Children star said that that although she loved having a career in TV and film, with MS, ‘all the things I thought were important shifted’.

“For a long time, it felt impossible to find the meaning in everything I’ve been through, but for the first time in my life, I’ve been able to stop and reflect. I’ve packed a lot into these 50-something years. It’s scary — not gonna lie — to finally decide to tell it all,” she explained.

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