Cromolyn, Mast Cells, and Neck Drama: The Unexpected Twist That’ll Make You Rethink Everything You Thought You Knew!
Added on September 21, 2025 inASTROLOGY CARDS
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Ever wonder if your body might be sending you secret messages disguised as endless doctor visits and baffling diagnoses? Well, buckle up, because what I thought was the last puzzle piece—neck surgery to fix a seriously twisted spine—turns out to be just the prelude to a rollercoaster ride starring none other than my unruly mast cells. Yeah, those little immune troublemakers flaring up like Mercury in retrograde chaos, wreaking havoc in places I never imagined—like my bladder, for instance. Turns out, what felt like a lifelong battle with bladder issues was actually a mast cell mess all along, and those pricey pills? They were big pharma’s little plot twist, not my miracle cure. So, if you’re curious how a cascade of histamines can hijack your life and why tuning into your body’s whispers might just save you years of misery, you’re in the right place. Ready to explore the cosmic connection between your health and hidden triggers? Let’s dive in. LEARN MORE
I’ve had an astoundingly fast turnaround in regards to my health. I am idiotic enough to have thought, once I had my neck stabilized, that was going to be it! Everything would be resolved! I’ve learned otherwise, but the news is still good.
The surgery itself is traumatic and activating. My neck was curved backwards. It’s now straight and this is foreign to me. Nerves are frazzled, things have heal, bones have to fuse and blah, blah, blah. As long as I’m in this state, my Mast Cells are going to flare, to be knocked down, over and over by the Cromolyn Police Force. There is a difference already. I no longer suffer the “dumping”, I mentioned, which was exhausting. But the final results are not in and won’t be for least a couple months. I expect the problems that remain to just slowly resolve, now with a few exceptions and/or unknowns.
Halfway through all this, I realized that outside of issues with my spine, every single problem I have had for the last fifteen years, has been related to mast cells and mast cells alone. If you knew how many appointments I have had, you’d faint. I have been tested for MS, put on antibiotics for nine months, diagnosed with Lupus, given a “full body cancer scan”, had not one, but two brain MRI’s; this is in addition to all my spine stuff.
I have also been medicated to high heaven, round the block up there, before I arrived where I am now; I’ve traded polypharmacy for Cromolyn only! I’ve traded my misery as well. All the drugs made me sick(er) and it’s worse that that. Some of the drugs left me with permanent damage.
I warn you, this is disturbing. I was put on a drug (Ditropan XL) for overactive bladder in my thirties. You can read about how this happened, here: Ladies, Let’s Talk About Your Bladder Issues! I was going to go into this, deeply, but I just don’t have the energy.
Here’s the bottom line. I took this drug and drugs like if for 23 years! I took the Oxybuytin for ten years, then double the does for another eight years or so, then switched to, Mybetric (roughly $17 a pill/$17 a day). Finally, I was put on “Gemtessa”, same high cost… I was so sick I told my doctor, “Hey. I don’t care if I sit on the toilet and type all day, because I feel I have to pee, when I don’t have to pee. Nothing is worse than this.” I was sobbing.
So I went off these drugs and guess what? I don’t have a bladder problem! 23 years of pills I don’t need.
This is the drug that caused my left hand to fall off the keyboard and many other horrific symptoms, I will spare you hearing about. I will say, the brain MRI were ordered, because they were looking for a stroke. I had the symptoms, but I had a stroke. I mean, I could not even write my name at one point. My first name! I could not write E-L-S-A on a piece of paper. This was a side effect of these drugs! I quick taking them and guess what? I was able to write my name within a week.
Now, you’re not me, but I want you to know, at the end of all this diagnosing, I had to ask, AI: “What about gemtessa and other bladder drugs with this profile?” Sure enough, there is a direct correlation:
Mast Cell Activation: A trigger (which could be stress, a certain food, a chemical scent, etc.) causes the unstable mast cells in the bladder wall to degranulate—meaning they burst open and release their inflammatory mediators.
Chemical Irritation: The primary chemical, histamine, along with others, bathes the surrounding bladder tissue and nerves.
Effects on the Bladder:
Muscle Contraction: These chemicals directly cause the detrusor muscle (the muscle that squeezes the bladder to empty it) to contract involuntarily. This creates the sudden, urgent need to urinate.
Nerve Sensitivity: The chemicals also hypersensitize the local nerves that signal bladder fullness to the brain. The brain then receives “full” signals even when the bladder is only slightly filled, leading to frequency and urgency.
In many cases, what appears to be a primary bladder disorder (OAB) is actually a secondary symptom of underlying mast cell activation. Treating the MCAS (with mast cell stabilizers, antihistamines, and trigger avoidance) can often calm the bladder inflammation and significantly reduce or eliminate the OAB symptoms. In short: MCAS causes bladder symptoms by turning the bladder into an inflamed, irritated, and hypersensitive environment through the constant release of histamine and other inflammatory chemicals.
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This was the coup de grace. This problem has been life-ruining for me for 25 years!
If you click over, you will see these drugs are big money makers. I didn’t need a bladder drug. I needed a mast cell stabilizer. It’s a travesty. I have been healthy (but chronically irritated) this entire time.
This is all I can stand to write for now. I recommend you pay close attention to your body, and carefully mind the effects every drug you give it. I have lost a good many years of my life to this. No doctor has the time (or motivation) to do this for you. Do it yourself!
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